The liver is the largest solid organ in the body, the largest being the skin. It is also the heaviest gland in the body. Weighing about 1.5kg and measuring roughly 18 cm across and 15 cm deep. It is situated in the upper abdominal cavity, slightly inferior to the diaphragm and anterior to the stomach. 

The liver is an essential organ and you would die within 24 hours if it stopped working. With an estimated 500 functions it is a complex, multipurpose organ with a biosynthetic chemical function including:

  • detoxification.
  • bile synthesis.
  • excretion of bilirubin.
  • making plasma proteins.
  • storage of vitamins and glucose.
  • lipid, protein and carbohydrate metabolism.

Behind the liver lies the gallbladder, which stores the bile synthesized by the liver.

location of liver in bodyThe liver is remarkably resilient and the human body can lose up to two thirds without any significant effects. Following the loss of part of the liver volume the remaining liver will enlarge. A discovery that made modern liver surgery and transplantation a reality.


Figure: The liver in the abdominal cavity 

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Liver disease killing more Scots

02/12/2008 14:08
New statistics show that the number of deaths from alcoholic liver disease has overtaken those from heart attacks in some deprived areas. Read the full story at


Children 'risking liver disease'

22/11/2008 13:19
Binge drinking by children and teenagers is going to cause an increase in liver related health problems, a charity has warned. Read more at:


Frozen liver transplant success

01/10/2008 17:00
Scientists have managed to successfully freeze, thaw and transplant a pig's liver, bringing the technique one step closer for humans. Read more at:


Did you know...

Your liver holds approximately 13% (about one pint ) of your total blood supply at any given moment and is believed to have over 500 functions.